Letter by Di Bella et al Regarding Article, “Effect of Combined Systolic and Diastolic Functional Parameter Assessment for Differentiation of Cardiac Amyloidosis From Other Causes of Concentric Left Ventricular Hypertrophy”
To the Editor:
We read with great interest the article by Liu et al1 about the combined role of systolic septal longitudinal base-to-apex strain gradient and diastolic deceleration time of early filling in differentiating cardiac amyloidosis (CA) from other causes of concentric left ventricular hypertrophy (arterial hypertension, Fabry disease, and Friedreich’s ataxia).
Myocardial function is a complex physiological event because of radial, circumferential, and longitudinal deformation that can be explored by 2-dimensional (2D)-strain echocardiography, tagging MRI, and sonomicrometry.
Recently, we have analyzed the epicardial and endocardial deformation by 2D-strain echocardiography in patients with …