Letter by Alter Regarding Article, “Myocardial Fibrosis as a Key Determinant of Left Ventricular Remodeling in Idiopathic Dilated Cardiomyopathy: A Contrast-Enhanced Cardiovascular Magnetic Study”
To the Editor:
Late gadolinium enhancement (LGE) as assessed by MRI is a frequent finding in various cardiac diseases. While delineating postinfarct scar accurately, there are controversies on causes and consequences in dilative cardiomyopathy (DCM). The thorough study by Masci et al1 examined absence of LGE and deduced nonexistence of myocardial fibrosis as prognostic predictor of a favorable left ventricular (LV) remodeling in 58 patients with DCM. Of note, patients’ medical heart failure therapy was optimized after enrollment in the study.
For interpretation of LGE, differentiation of a variety of types and forms seems to be required. In particular, the most common streaky-like occurrence in DCM …