Letter by Scholtens et al Regarding Article, “Characterization of 18F-Fluorodeoxyglucose Uptake Patterns in Noninfected Prosthetic Heart Valves”
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To the Editor:
We read with great interest the recent article by Mathieu et al1 on 18F-fluorodeoxyglucose (FDG) uptake patterns in noninfected prosthetic heart valves (PHVs). Although FDG positron emission tomography (PET) with computed tomography (CT) has been incorporated in the latest version of the European Society of Cardiology guidelines for the management of infective endocarditis,2 there is still much that requires further clarification about this technique in this challenging setting, and a firm understanding of normal variation is of exceptional importance.
Of particular interest are the standardized uptake values (SUVs) that seem exceptionally high when compared with the other findings. Figure 3 in the study by Mathieu et al shows that …