Coronary Artery Plaque Burden Nomograms
Are They Ready for Use?
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- computed tomography angiography
- myocardial infarction
- myocardial revascularization
Coronary computed tomography angiography (CCTA) is frequently used in symptomatic patients to exclude the presence of obstructive coronary artery disease. Beyond high diagnostic accuracy, it provides valuable prognostic information. There is accumulating evidence that a patient’s risk of major adverse events is not solely due to the presence of obstructive coronary artery disease but also to the presence of nonobstructive atherosclerotic disease. In this light, CCTA has a definite advantage over invasive angiography because it provides information on plaque volume and composition beyond luminal stenosis.1 Currently, CCTA is the only noninvasive method available in everyday clinical practice capable of providing such information.
See Article by Naoum et al
Several reports on the prognostic value of CCTA demonstrated a stepwise increase in the risk of events from absence of coronary atherosclerosis, to presence of nonobstructive atherosclerosis, to obstructive coronary artery disease.2–4 It would seem, therefore, that CCTA provides confirmation of the tenet that the burden of atherosclerosis is prognostically significant beyond the presence of obstructive luminal disease. In this issue of Circulation: Cardiovascular Imaging, Naoum et al5 report on a new …