Quantification of Left Ventricular Size and Function by 2-Dimensional Echocardiography: So Basic and So Difficult
How to Increase the Accuracy and Reproducibility in Children?
This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
The evaluation of left ventricular (LV) dimensions, area, volumes, and function by 2D echocardiography is challenging. Quantification of LV chamber size and function is an essential and routine part of echocardiographic examination at all ages and in all settings.1,2 However, these fundamental measurements, although often critical for clinical decision making, are often subject to significant variability, especially in the pediatric age group.3–6 If a measurement is not accurate or reproducible, it may be difficult to be sure whether it is normal or not and also hard to follow the trend over time.3–6 Interpretation of an echocardiographic measurement over time should take into account several biases. An incomplete list of these potential biases includes (1) measurement accuracy (ie, Do we measure it in the same way? How much the final result will be affected by different measurement approaches?), (2) measurement reproducibility (how standardized a measurement varies according to different observers, and how standardized imaging collection varies according to different operators/repeated observation by the same operator), (3) physiological variation (How the variation over time is related to growth and age/body size changes?), (4) disease-related variations (How much the variation is pathological?), and (5) environment (patient cooperation/sedation; To what extent variations in basic parameters [ie, heart rate, blood pressure, and loadings conditions] influence our measurements?).
See Article by Selamet Tierney et al
– The issue of measurement accuracy and the clear need of standardization in pediatric echocardiography have been widely debated in the past few years.2,7,8 As a result of the 2010 recommendations of the American Society of Echocardiography,2 there is now sufficient standardization of measurements. However, LV volume and function quantification remains a controversial topic with …